Utiva provides a pure source of D-Mannose in convenient 500 mg capsules. D-Mannose has the ability to prevent E. coli from sticking to the bladder and urinary tract.

Ingredients

Per Capsule

Medicinal Ingredients

Each capsule contains D-Mannose - 500 mg

Non-Medicinal Ingredients

Microcrystalline cellulose, magnesium, stearate, hypermellose.

Adults take 2 capsules twice a day.
Consult a healthcare practitioner prior to use if you are pregnant or breastfeeding, if you have urinary tract anomalies, interstitial cystitis, diabetes or are taking hormone therapy/contraception, if you have fever, painful urination (dysuria), spasms or blood in urine, or if symptoms persist or worsen.

What is D-mannose and how does it work?

D-Mannose is a naturally occurring sugar that can help stop bacteria from adhering to the bladder wall, reducing the risk of infection. It is specifically effective against E. coli.

  • D-Mannose is similar in shape to the mannosylated uroplakin receptors on the urinary tract wall. These receptors fit perfectly within E.coli's type 1 fimbriae.
  • When D-Mannose is present in sufficient amounts, it can bind to all the E.coli fimbriae and inhibit bacterial adhesion to the urothelium.
  • Natural flushing occurs as the bacteria is eliminated via urine out of the bladder.

What is D-mannose and how does it work?

D-Mannose is a naturally occurring sugar that can help stop bacteria from adhering to the bladder wall, reducing the risk of infection. It is specifically effective against E. coli.

  • D-Mannose is similar in shape to the mannosylated uroplakin receptors on the urinary tract wall. These receptors fit perfectly within E.coli's type 1 fimbriae.
  • When D-Mannose is present in sufficient amounts, it can bind to all the E.coli fimbriae and inhibit bacterial adhesion to the urothelium.
  • Natural flushing occurs as the bacteria is eliminated via urine out of the bladder.

Clinical studies

01

In a pilot study, D-mannose was shown to be effective at reducing recurrent UTIs.

4.5%

UTI recurrence rate in patients who received D-Mannose for 6 months.

02

In a clinical trial, D-mannose was shown to be effective at preventing UTIs.

48

out of 60 recurrent UTI patients were UTI free for a 24-week period with D-mannose.

03

In a randomized clinical trial, D-mannose powder had significantly reduced the risk of recurrent UTIs.

45%

absolute risk reduction for recurrent UTIs in patients who received D-mannose compared to control group.

Utiva is the #1 Doctor Recommended Brand

Canadian Healthcare Network

Utiva was voted the #1 most recommended brand for UTI prevention by doctors in Canada!

Can Utiva UTI Control and Utiva D-Mannose be taken together?

Although UTI Control and D-Mannose are individually approved by Health Canada for UTI prevention, it is recommended not to combine them in the same dose. Preliminary research shows there is decreased anti-adhesion activity of PACs from cranberries when taken at the same time as D-Mannose.

Urologist Dr. Curtis Nickel explains more during his lecture at the 2023 CUA meeting.

UTI prevention related talks

Dr. Susan Oakley
Shelley Morgan
Dr. Lysanne Campeau
Dr. Adam Holzberg
Dr. Susan Oakley
Dr. Bilal Chughtai
Dr. Yana Barbalat
Dr. Ashley Girard

For more information or wholesale inquiries, please feel free to reach out to us.

For more information or wholesale inquiries, please feel free to reach out to us.