36 mg

of proanthocyanidins (PACs) from cranberries.

• 50

  clinical studies on cranberries for UTI prevention.

• 67%

  reduction in the number of patients who experienced a UTI while receiving Utiva.

  ¹

  ⁽¹⁾ Dr. Donald Rowe (2020). Go to source

• 19%

  of patients post gynecologic surgery in the cranberry group experienced UTIs compared to 38% in the placebo group.

  ²

  ⁽²⁾ Foxman, B., Cronenwett, A. E. W., Spino, C., Berger, M. B., & Morgan, D. M. (2015). Cranberry juice capsules and urinary tract infection after surgery: Results of a randomized trial. American Journal of Obstetrics and Gynecology, 213(2). Go to source

• 36mg

  The CUA/AUA and Family Physicians Guidelines support the use of 36 mg PACs for UTI prevention.

500 mg

of D-mannose, a naturally occurring sugar.

• 3+

  studies on the use of D-Mannose for UTI prevention.

• 4.5%

  UTI recurrence rate in patients who received D-Mannose for 6 months.

  ³

  ⁽³⁾ Domenici L, Monti M, Bracchi C, Giorgini M, Colagiovanni V, Muzii L, Benedetti Panici P. (2016). D-mannose: a promising support for acute urinary tract infections in women. A pilot study. Eur Rev Med Pharmacol Sci. 20(13), 2920-5. Go to source

• 45%

  absolute risk reduction for recurrent UTIs in patients who received D-mannose compared to control group.

  ⁴

  ⁽⁴⁾ Kranjčec, B., Papeš, D., & Altarac, S. (2013). D-mannose powder for prophylaxis of recurrent urinary tract infections in women: A randomized clinical trial. World Journal of Urology, 32(1), 79–84. Go to source

• 48

  out of 60 recurrent UTI patients were UTI free for a 24-week period with D-mannose.

  ⁵

  ⁽⁵⁾ Porru, D., Parmigiani, A., Tinelli, C., Barletta, D., Choussos, D., Di Franco, C., Bobbi, V., Bassi, S., Miller, O., Gardella, B., Nappi, R., Spinillo, A., & Rovereto, B. (2014). Oral D-mannose in recurrent urinary tract infections in women: A pilot study. Journal of Clinical Urology, 7(3), 208–213. Go to source

30 Billion

CFU (at time of manufacture) unique blend of Lactobacillus & Bifidobacterium strains.

• 12+

  studies on Lactobacillus Rhamnosus GG for reducing antibiotic side effects.

• 45%

  reduction in the risk of antibiotic-related diarrhea in patients given L. rhamnosus GG.

  ⁶

  ⁽⁶⁾ Szajewska, H., & Kołodziej, M. (2015). Systematic review with meta-analysis: lactobacillus rhamnosus GG in the prevention of antibiotic-associated diarrhoea in children and adults. Alimentary Pharmacology Therapeutics, 42(10), 1149–1157. Go to source

• 75%

  risk reduction of C. difficile-associated diarrhea with probiotics containing Lactobacillus spp.

  ⁷

  ⁽⁷⁾ Sinclair, A., Xie, X., Saab, L., & Dendukuri, N. (2016a). Lactobacillus probiotics in the prevention of diarrhea associated with clostridium difficile: A systematic review and Bayesian hierarchical meta-analysis. CMAJ Open, 4(4). Go to source

• 4

  Health Canada approved claims

500 mg

of a proprietary full spectrum cranberry extract, Flowens®.

• 3+

  studies on Flowens for overactive bladder (OAB) and lower urinary tract symptoms (LUTS).

• 57%

  reduction in urgency episodes.

  ⁸

  ⁽⁸⁾ Cho, A., Eidelberg, A., Butler, D. J., Danko, D., Afshinnekoo, E., Mason, C. E., & Chughtai, B. (2021). Efficacy of daily intake of dried cranberry 500 mg in women with overactive bladder: A randomized, double-blind, placebo controlled study. Journal of Urology, 205(2), 507–513. Go to source

• 40%

  reduction in patient perception of bladder feeling full.

  ⁸

  ⁽⁸⁾ Cho, A., Eidelberg, A., Butler, D. J., Danko, D., Afshinnekoo, E., Mason, C. E., & Chughtai, B. (2021). Efficacy of daily intake of dried cranberry 500 mg in women with overactive bladder: A randomized, double-blind, placebo controlled study. Journal of Urology, 205(2), 507–513. Go to source

• 13

  Health Canada approved claims.

600 mg

of boric acid - a natural compound found in seawater and mineral-rich deposits in the earth.

• 16+

  studies demonstrated the efficacy of boric acid for treating vulvovaginal candidiasis.

• 55.3

  -100% success rate of patients given 600 mg of boric acid once or twice daily for 14 days.

  ⁹

  ⁽⁹⁾ Iavazzo, C., Gkegkes, I. D., Zarkada, I. M., & Falagas, M. E. (2011). Boric acid for recurrent vulvovaginal candidiasis: The clinical evidence. Journal of Women’s Health, 20(8), 1245–1255. Go to source

• 72.4%

  mycological cure with boric acid vaginal suppositories given for 14 days.

  ¹⁰

  ⁽¹⁰⁾ Ray, D., Goswami, R., Banerjee, U., Dadhwal, V., Goswami, D., Mandal, P., Sreenivas, V., & Kochupillai, N. (2007). Prevalence of candida glabrata and its response to boric acid vaginal suppositories in comparison with oral fluconazole in patients with diabetes and vulvovaginal candidiasis. Diabetes Care, 30(2), 312–317. Go to source

• 4

  Health Canada approved claims.

225 mg

of lactic acid.

• 20+

  studies on the safety and efficacy of lactic acid for managing yeast infections.

• 88%

  of symptom relief 6 months after treatment initiation with lactic acid.

  ¹¹

  ⁽¹¹⁾ Andersch, B., Lindell, D., Dahlén, I., & Brandberg, Å. (1990). Bacterial Vaginosis and the Effect of Intermittent Prophylactic Treatment with an Acid Lactate Gel. Gynecologic and Obstetric Investigation, 30(2), 114–119. Go to source

• 7

  days after treatment initiation, lactate gel demonstrated equal efficacy in comparison to treatment with metronidazole with no adverse side effects.

  ¹²

  ⁽¹²⁾ Andersch, B., Forssman, L., Lincoln, K., & Torstensson, P. (1986). Treatment of Bacterial Vaginosis with an Acid Cream: A Comparison between the Effect of Lactate-Gel and Metronidazole. Gynecologic and Obstetric Investigation, 21(1), 19–25. Go to source

• 11

  Health Canada approved claims.

605 mg

softgel containing CO2-extracted saw palmetto and beta-sitosterol, carefully sourced from plants.

• 9+

  studies on saw palmetto and beta-sitosterol for supporting healthy prostate function.

• 12

  week treatment with beta-sitosterol enriched saw palmetto oil decreased symptoms of benign prostatic hyperplasia significantly.

  ¹³

  ⁽¹³⁾ Sudeep, H. V., Thomas, J. V., & Shyamprasad, K. (2020a). A double blind, placebo-controlled randomized comparative study on the efficacy of phytosterol-enriched and conventional saw palmetto oil in mitigating benign prostate hyperplasia and androgen deficiency. BMC Urology, 20(1). Go to source

• 91%

  reduction of prostate growth when given beta-sitosterol enriched saw palmetto oil.

  ¹⁴

  ⁽¹⁴⁾ Sudeep, Heggar V., Venkatakrishna, K., Amrutharaj, B., Anitha, & Shyamprasad, K. (2019). A phytosterol-enriched saw Palmetto Supercritical CO2 extract ameliorates testosterone-induced benign prostatic hyperplasia by regulating the inflammatory and apoptotic proteins in a rat model. BMC Complementary and Alternative Medicine, 19(1). Go to source

• 85

  -95% fatty acid content to match United States Pharmacopeia guidelines.