Clinical Studies
We’re committed to providing formulations with ingredients that have demonstrated clear effectiveness in clinical trials. Please note this research has been conducted by a variety of sources. We at Utiva have compiled all relevant studies to support the use of the ingredients in our products.
UTI CONTROL
Does cranberry have a role in catheter-associated urinary tract infections?
Evaluating the efficacy of an oral cranberry supplement with 36 mg of PACs on patients with long-term indwelling catheters and recurrent symptomatic CA-UTIs.
Prevention of urinary tract infection with oximacro, a cranberry extract with a high content of A-type proanthocyanidins
Using a cranberry extract with a high content of PAC-A to prevent UTIs in female and male volunteers.
Are high proanthocyanidins key to cranberry efficacy in the prevention of recurrent urinary tract infections?
Testing whether whole cranberry fruit powder could prevent recurrent UTI in 182 women with two or more UTI episodes in the last year.
Dosage effect on uropathogenic Escherichia coli anti-adhesion activity in urine following consumption of cranberry powder standardized for proanthocyanidin content
Investigating the most effective dose of PACs per day and determining if the urinary anti-adhesion effect following cranberry is detected within patients.
Study Trial for reduction in recurrent UTIs in long term care patients using daily high concentration cranberry extract 36mg proanthocyanidin capsules
A case study to evaluate the efficacy of a natural cranberry extract with high PAC concentration to reduce UTIs in long term care patients
Cranberries for preventing urinary tract infection
A review of all randomized controlled trials (RCTs) or quasi‐RCTs of cranberry products for the prevention of UTIs.
Cranberry or trimethoprim for the prevention of recurrent urinary tract infections?
Comparing the effectiveness of cranberry extract with low-dose trimethoprim in the prevention of recurrent UTIs in older women.
Cranberry juice capsules and urinary tract infection after surgery: results of a randomized trial
We sought to determine the efficacy of dried cranberry on reducing symptoms of overactive bladder in women.
D-MANNOSE
D-mannose: a promising support for acute urinary tract infections in women. A pilot study
Determining whether D-mannose alone is effective in treating acute UTIs in women and its possible utility in the management of recurrences.
D-mannose powder for prophylaxis of recurrent urinary tract infections in women: a randomized clinical trial
Testing whether D-mannose powder is effective for recurrent UTI prevention in comparison to Nitrofurantoin.
Oral D-mannose in recurrent urinary tract infections in women: a pilot study
Evaluating the efficacy of D-mannose in the treatment and prophylaxis of recurrent UTIs.
PROBIOTIC
Systematic review with meta-analysis: Lactobacillus rhamnosusGG in the prevention of antibiotic-associated diarrhea in children and adults
Evaluating the efficacy of Lactobacillus rhamnosus GG (LGG) in the prevention of antibiotic-associated diarrhea (AAD) in children and adults.
Antagonistic activity of probiotic lactobacilli and bifidobacteria against entero‐ and uropathogens
Screening Lactobacillus and Bifidobacterium sp. strains according to their activity in various environmental conditions.
Lactobacillus probiotics in the prevention of diarrhea associated with Clostridium difficile
Systemic review evaluating the efficacy of probiotics for preventing diarrhea associated with Clostridium difficile.
BLADDER CONTROL
Efficacy of Daily Intake of Dried Cranberry 500 mg in Women with Overactive Bladder
Determining the efficacy of dried cranberry on reducing symptoms of overactive bladder in women.
Cranberry fruit powder (Flowens™) improves lower urinary tract symptoms in men
Evaluating the dose effect of 250 or 500 mg cranberry powder (Flowens™) on LUTS and uroflowmetry.
YEAST CONTROL
Boric acid for recurrent vulvovaginal candidiasis: the clinical evidence
Investigating the clinical evidence on the intravaginal use of boric acid for vulvovaginal candidiasis.
Prevalence of Candida glabrata and its response to boric acid vaginal suppositories in comparison with oral fluconazole in patients with diabetes and vulvovaginal candidiasis
Evaluating the response to oral fluconazole and boric acid vaginal suppositories in diabetic patients with vulvovaginal candidiasis.
Fluconazole-resistant Candida albicans vaginal infections at a referral center and treated with boric acid
Investigating the incidence of clinical and mycological resistance of Candida albicans vulvovaginitis.
Boric acid and commercial organoboron products as inhibitors of drug-resistant Candida albicans
Assessing the clinical use of boric acid against drug-resistant Candida albicans.
BACTERIAL VAGINOSIS RELIEF
Bacterial vaginosis and the effect of intermittent prophylactic treatment with an acid lactate gel
Local intermittent application of lactate gel as an alternative to repeated treatments with antibiotics in patients with recurrent bacterial vaginosis.
Treatment of bacterial vaginosis with an acid cream: a comparison between the effect of lactate-gel and metronidazole
Evaluating anaerobes levels in women after treatment with lactate gel for bacterial vaginosis.
PROSTATE HEALTH
A double blind, placebo-controlled randomized comparative study on the efficacy of phytosterol-enriched and conventional saw palmetto oil in mitigating benign prostate hyperplasia and androgen deficiency
Evaluating the efficacy and tolerability of a standardized saw palmetto oil containing β-sitosterol in the treatment of BPH and androgen deficiency.
A phytosterol-enriched saw palmetto supercritical CO2 extract ameliorates testosterone-induced benign prostatic hyperplasia by regulating the inflammatory and apoptotic proteins in a rat model
Comparing β-sitosterol enriched saw palmetto oil to conventional saw palmetto oil preparations in efficacy for treating the BPH complications.
